Pathogenesis of muscle weakness in inflammatory myositis
نویسندگان
چکیده
منابع مشابه
O 28: Autoimmune Myositis: General Aspects of Pathophysiology, Symptoms and Therapeutic Options
Idiopathic inflammatory myopathies are a heterogeneous group of muscle disorders characterized by chronic muscle inflammation and progressive muscle weakness. Polymyositis (PM), dermatomyositis (DM) and inclusion body myositis (IBM) are the three major subsets based on distinct clinical and histopathological features. Since the pathogenesis remains unclear, therapeutic approaches actually compr...
متن کاملCase report Myositis associated graft-versus-host-disease presenting as respiratory muscle weakness
Myositis associated with graft-versus-hostdisease (GVHD) typically presents with proximal muscle weakness, myalgias, and a raised creatinine phosphokinase (CPK) level. We report a case of a 51 year old man who developed respiratory muscle weakness five years after an allogeneic bone marrow transplant for multiple myeloma. His symptoms included tachypnoea, abdominal paradox, and orthopnoea. Pulm...
متن کاملMyositis associated graft-versus-host-disease presenting as respiratory muscle weakness.
Myositis associated with graft-versus-host-disease (GVHD) typically presents with proximal muscle weakness, myalgias, and a raised creatinine phosphokinase (CPK) level. We report a case of a 51 year old man who developed respiratory muscle weakness five years after an allogeneic bone marrow transplant for multiple myeloma. His symptoms included tachypnoea, abdominal paradox, and orthopnoea. Pul...
متن کاملMuscle Weakness
Marked ligamentous hyperlaxity and muscle weakness/wasting associated with awkward gait are the main deficits confused with the diagnosis of myopathy. Seven children (6 boys and 1 girl with an average age of 8 years) were referred to our department because of diverse forms of skeletal abnormalities. No definitive diagnosis was made, and all underwent a series of sophisticated investigations in ...
متن کاملPathogenesis and therapy of inclusion body myositis.
PURPOSE OF REVIEW Inclusion body myositis (IBM) is a poorly understood progressive muscle disease of middle and later life. Its dual pathologies of autoimmunity and unexplained myofiber degeneration and loss have been enigmatic since its earliest descriptions over 40 years ago. No reliable effective therapy currently exists for IBM. This review provides an update of current issues in the pathog...
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ژورنال
عنوان ژورنال: Indian Journal of Rheumatology
سال: 2020
ISSN: 0973-3698
DOI: 10.4103/injr.injr_120_20